Antibodies, A Laboratory Manual, Second Edition, Edited by Edward A. Greenfield



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Preparing Cell Smears from Tissue Samples or Cell Cultures

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Cell staining can be performed on cell smears prepared from biopsy samples, such as needle aspirates, tissue scrapings, or freshly dissected tissues. In these protocols, a thin layer of cells is deposited on a dry slide by physical methods. The most important factor in obtaining good staining patterns is that the smear be only a single cell thick. Tissue smears do not preserve tissue architecture, but are useful for identifying pathological changes and infectious organisms in tissue samples.

Antibodies: A Laboratory Manual, Second edition
Antibodies: A Laboratory Manual, Second edition
Antibodies: A Laboratory Manual, Second edition

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